Methods: Patients with a tissue diagnosis of breast cancer who did not have metastasis, and were candidates for either breast conservation surgery (BCS) and sentinel lymph node biopsy (SLNB) with or without axillary lymph node dissection (ALND), or modified radical mastectomy (MRM) were included in a prospective study. Patients were randomly allocated to one of the above mentioned three groups. The incidence of seroma formation was compared among the groups.
Results: Sixty patients (age: 50.25 ± 10.33 years) were enrolled for the study. At the end of the study, after four weeks of postoperative follow up, 19 patients developed seroma (31.6%), of whom 5 (26.3%) had dissection with harmonic scissors, 6 (31.5%) with Metzenbaum scissors, and 8 (42.1%) were dissected bluntly. There was no significant difference among groups regarding seroma formation (P = 0.583).
Conclusion: Application of harmonic scissors for axillary dissection has no significant impact on seroma formation. However, MRM leads to significantly more seroma formation compared with BCS.
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Copyright (c) 2018 Archives of Breast Cancer
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