Clinical and Diagnostic Study of Breast Cancer in Women and its Relation with Periodontal Disease BC in relation to periodontal disease
Abstract
Background: Breast cancer (BC) is a common type of malignancy in females in Iraq. This study investigated BC's clinical and diagnostic features in 30 women and displayed its relationship with periodontal disease.
Methods: This cross-sectional study comprised 30 BC patients diagnosed in 2023. The clinical signs, ultrasound, biopsy, histopathology and Immunohistochemistry, treatment modules, and clinical signs of periodontal disease were reported and analyzed.
Results: The mean and standard deviation of patients’ age was 51.73± 11.41. The location of Breast Cancer lesions was on the left and right sides in 11 (36.66%) and 19 (63.33%) patients, respectively. All patients showed various sizes of non-painful lumps with well-defined masses in different areas of the breast tissue with regular or irregular borders in ultrasound and MRI. The gross and histopathological changes of cancerous tumors differed according to conditions, stage, and interaction with the cancer receptors in Immunohistochemistry. The percentage of metastases was 100% (in 30 cases) for the lymph nodes and 66.66% (in 20 cases) for the rest of the other organs. Different treatment modules were used, including chemotherapy, surgery, radiation, and hormonal therapy. The cases suffering from mild, moderate, and severe periodontal disease were 7 (23.33 %), 2 (6.66%), and 21 (70%), respectively.
Conclusion: The clinical signs, histopathological, IHC, and occurrence of periodontal disease in 30 women with breast cancer were documented in this study. The authors recommend further studies on breast cancer to support its early diagnosis and prevention strategies.
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