Anaplastic Large Cell Lymphoma Associated with Saline Breast Implant

Grace Ng (1), Rupa K. Patel (2), LaNette Smith (3), Guido Sclabas (4)
(1) Department of Surgery, School of Community Medicine, University of Oklahoma, Oklahoma, USA,
(2) Department of Surgery, School of Community Medicine, University of Oklahoma, Oklahoma, USA,
(3) Breast Surgery of Tulsa, Oklahoma, USA,
(4) Department of Surgery, School of Community Medicine, University of Oklahoma, Oklahoma, USA
https://doi.org/10.19187/abc.201634135-138

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Issue
Vol 3, No 4: November 2016
Submitted
September 10, 2016
Published
December 3, 2016
Keywords:
    breast lymphoma, breast implant, seroma
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Abstract

Background: Breast implant associated anaplastic large T- cell lymphoma is a rare type of non-Hodgkin lymphoma, with a reported incidence of 0.3% per 100,000 women with breast prosthesis per year. It presents most commonly as a peri-implant seroma, but may also present as a capsular mass, tumor erosion through skin, in a regional lymph node, or found incidentally during revision surgery.

Case presentation: We report a 68-year-old female patient who presented with a four month history of marked pain and swelling of the right breast, who upon implant removal and right sided capsulectomy, revealed pathology consistent with ALK negative, CD 30 positive anaplastic large T- cell lymphoma.

Conclusion: Breast implant associated anaplastic large cell lymphoma, although a rare clinical occurrence is of clinical significance. Prognosis is favorable in the majority of reported cases. Definitive treatment guidelines have yet to be determined after review of long-term follow-up data.

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Authors

Grace Ng
Department of Surgery, School of Community Medicine, University of Oklahoma, Oklahoma, USA
grace-ng@ouhsc.edu (Primary Contact)
Rupa K. Patel
Department of Surgery, School of Community Medicine, University of Oklahoma, Oklahoma, USA
LaNette Smith
Breast Surgery of Tulsa, Oklahoma, USA
Guido Sclabas
Department of Surgery, School of Community Medicine, University of Oklahoma, Oklahoma, USA
1.
Ng G, Patel RK, Smith L, Sclabas G. Anaplastic Large Cell Lymphoma Associated with Saline Breast Implant. Arch Breast Cancer [Internet]. 2016 Dec. 3 [cited 2025 Jan. 9];3(4):135-8. Available from: https://archbreastcancer.com/index.php/abc/article/view/99
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