Quality of Life Assessment After Conserving Breast Surgery and  Intraoperative Radiotherapy (IORT) in Breast Cancer Patients  Using the BREAST-Q Questionnaire

Marina Caldana; Davide Lombardi; Silvia Urbani; Francesca Pellini; Sara Mirandola; Eleonora Granuzzo; Giovanni Paolo Pollini

doi:10.32768/abc.202074183-188

Marina Caldana ⁽¹⁾, Davide Lombardi ⁽²⁾, Silvia Urbani ⁽³⁾, Francesca Pellini ⁽⁴⁾, Sara Mirandola ⁽⁵⁾, Eleonora Granuzzo ⁽⁶⁾, Giovanni Paolo Pollini ⁽⁷⁾

(1) a Operative Unit of Breast Surgery Complex, Breast Unit, Oncologic Surgery Department, AOUI, Verona, Italy, Italy,

(2) a Operative Unit of Breast Surgery Complex, Breast Unit, Oncologic Surgery Department, AOUI, Verona, Italy, Italy,

(3) a Operative Unit of Breast Surgery Complex, Breast Unit, Oncologic Surgery Department, AOUI, Verona, Italy, Italy,

(4) a Operative Unit of Breast Surgery Complex, Breast Unit, Oncologic Surgery Department, AOUI, Verona, Italy, Italy,

(5) a Operative Unit of Breast Surgery Complex, Breast Unit, Oncologic Surgery Department, AOUI, Verona, Italy, Italy,

(6) a Operative Unit of Breast Surgery Complex, Breast Unit, Oncologic Surgery Department, AOUI, Verona, Italy, Italy,

(7) a Operative Unit of Breast Surgery Complex, Breast Unit, Oncologic Surgery Department, AOUI, Verona, Italy, Italy

https://doi.org/10.32768/abc.202074183-188

Issue
Vol 7, No 4: November 2020

Submitted
September 21, 2020

Published
November 16, 2020

Keywords:

Breast Cancer, Patient-reported outcome measures, BREAST-Q, Breast conserving surgery, Intraoperative radiotherapy, IORT

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Abstract

Background: In women undergoing breast surgery, Measurement of Patient Related Outcome Measures (PROMs) is important for improving the process of care, focusing on the patient's perspective. BREASTQ is a validated patient-reported outcome measure used increasingly in aesthetic and recostructive surgery. Only recently a breast conserving therapy module (BREASTQ-BCT) has been available. The aim of this study was to assess patient satisfaction and quality of life using BREAST-Q questionnaire in patients undergoing breast conserving surgery (BCS) plus IORT.
Methods: Women undergoing BCS plus IORT for an early-stage breast cancer for at least a year were invited by telephone to partecipate. We scheduled dedicated outpatient visits to our center. The medical interviewer collected medical history information and administered the BREASTQ-BCT in paper format. Data were inserted in a de-identified database. Univariate regression analysis was used to identify clinicopathological variables associated with "satisfaction with breast" domain score.
Results: Overall, 38 women completed the questionnaire. The domains of the questionnaire that obtained the lowest scores were ‘satisfaction with IORT information’ and ‘satisfaction with breasts’ (median score 59, IQR 55-73 and 51-69.5). Weight of specimen and vascular invasion were risk factors for lower ‘Satisfaction with breasts’ at univariate analysis. There was a moderate-strong correlation between 'satisfaction with the breasts' and 'psychosocial wellbeing' and 'Sexual wellbeing'.
Conclusions: In this retrospective study, without a pre-operative questionnaire, changes in individuals’ satisfaction and quality of life could not be identified. A prospective study comparing BCS plus external RT group and BCS plus IORT group could be informative.

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